A Genetic and Developmental Analysis of a Soluble Acid Deoxyribonuclease in Drosophila melanogaster

Charles Detwiler; Ross MacIntyre

A Genetic and Developmental Analysis of a Soluble Acid Deoxyribonuclease in Drosophila melanogaster

School of Health Sciences

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Abstract

A deoxyribonuclease, called DNase-1, that is active at acid pH in the presence of EDTA has been studied in Drosophila melanogaster. The locus for the enzyme maps genetically to 61.8 on the right arm of the third chromosome. Cytogenetically, DNase-1 has been localized to within five to ten bands between 90C-2 and 90E. This analysis utilizes both electrophoretic variants and the Y-autosome translocations of Lindsley et al. (1972). DNase-1 is present in all stages of the life cycle, and the paternal genome actively contributes DNase-1 to the embryo between 0 and 1 hr after fertilization.

Original language	American English
Journal	Biochemical Genetics
Volume	16
State	Published - Jan 1 1978

Keywords

Drosophila melanogaster
isozymes
position effect
segmental aneuploidy

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abstract = " A deoxyribonuclease, called DNase-1, that is active at acid pH in the presence of EDTA has been studied in Drosophila melanogaster. The locus for the enzyme maps genetically to 61.8 on the right arm of the third chromosome. Cytogenetically, DNase-1 has been localized to within five to ten bands between 90C-2 and 90E. This analysis utilizes both electrophoretic variants and the Y-autosome translocations of Lindsley et al. (1972). DNase-1 is present in all stages of the life cycle, and the paternal genome actively contributes DNase-1 to the embryo between 0 and 1 hr after fertilization.",

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T1 - A Genetic and Developmental Analysis of a Soluble Acid Deoxyribonuclease in Drosophila melanogaster

AU - Detwiler, Charles

AU - MacIntyre, Ross

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N2 - A deoxyribonuclease, called DNase-1, that is active at acid pH in the presence of EDTA has been studied in Drosophila melanogaster. The locus for the enzyme maps genetically to 61.8 on the right arm of the third chromosome. Cytogenetically, DNase-1 has been localized to within five to ten bands between 90C-2 and 90E. This analysis utilizes both electrophoretic variants and the Y-autosome translocations of Lindsley et al. (1972). DNase-1 is present in all stages of the life cycle, and the paternal genome actively contributes DNase-1 to the embryo between 0 and 1 hr after fertilization.

AB - A deoxyribonuclease, called DNase-1, that is active at acid pH in the presence of EDTA has been studied in Drosophila melanogaster. The locus for the enzyme maps genetically to 61.8 on the right arm of the third chromosome. Cytogenetically, DNase-1 has been localized to within five to ten bands between 90C-2 and 90E. This analysis utilizes both electrophoretic variants and the Y-autosome translocations of Lindsley et al. (1972). DNase-1 is present in all stages of the life cycle, and the paternal genome actively contributes DNase-1 to the embryo between 0 and 1 hr after fertilization.

KW - Drosophila melanogaster

KW - isozymes

KW - position effect

KW - segmental aneuploidy

UR - https://digitalcommons.liberty.edu/bio_chem_fac_pubs/60

M3 - Article

VL - 16

JO - Biochemical Genetics

JF - Biochemical Genetics

ER -

A Genetic and Developmental Analysis of a Soluble Acid Deoxyribonuclease in Drosophila melanogaster

Abstract

Keywords

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