TY - CONF
T1 - The effect of omega-3 fatty acids derived from krill protein concentrate on tissue deposition and lipid peroxidation
AU - Bridges, Kayla
AU - Gigliotti, Joseph C.
AU - Jaczynski, Jacek
AU - Tou, Janet C
N1 - If the address matches an existing account you will receive an email with instructions to reset your password
PY - 2009/4
Y1 - 2009/4
N2 - Krill protein concentrate (KPC) has been determined to be a high quality protein for human consumption with the advantage of being a rich source of the omega-3 polyunsaturated fatty acids (ω-3 PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). The ω-3 PUFAs in krill oil are mainly associated with phospholipids, which have been proposed to result in high incorporation of ω-3 PUFAs into tissues and to be stable against oxidation. The study objective was to determine tissue deposition and oxidative stability of ω-3 PUFAs in rats fed KPC. Young female Sprague-Dawley rats (n=10/group) were fed ad libitum isocaloric diets with either 10% freeze-dried KPC (~8% oil) containing 4.4% corn oil (KPC + CO) or 10% casein containing 5.3% corn oil (C + CO) for 4 weeks. Fatty acid compositions of various tissues were analyzed by gas chromatography. Lipid peroxidation was determined by TBARS and total antioxidant capacity by enzyme immunoassay. The study results showed even at a KPC contribution of 0.9% lipids to the total diet, EPA and DHA content increased (P<0.01) in adipose and liver tissue while decreasing (P<0.01) the ω-6 PUFA, arachidonic acid. There was no significant difference in brain tissue deposition of ω-3 PUFAs, total antioxidant capacity, or lipid peroxidation between groups. Based on the study results, ω-3 PUFAs associated with KPC resulted in tissue incorporation without changing oxidative stability.
AB - Krill protein concentrate (KPC) has been determined to be a high quality protein for human consumption with the advantage of being a rich source of the omega-3 polyunsaturated fatty acids (ω-3 PUFAs), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). The ω-3 PUFAs in krill oil are mainly associated with phospholipids, which have been proposed to result in high incorporation of ω-3 PUFAs into tissues and to be stable against oxidation. The study objective was to determine tissue deposition and oxidative stability of ω-3 PUFAs in rats fed KPC. Young female Sprague-Dawley rats (n=10/group) were fed ad libitum isocaloric diets with either 10% freeze-dried KPC (~8% oil) containing 4.4% corn oil (KPC + CO) or 10% casein containing 5.3% corn oil (C + CO) for 4 weeks. Fatty acid compositions of various tissues were analyzed by gas chromatography. Lipid peroxidation was determined by TBARS and total antioxidant capacity by enzyme immunoassay. The study results showed even at a KPC contribution of 0.9% lipids to the total diet, EPA and DHA content increased (P<0.01) in adipose and liver tissue while decreasing (P<0.01) the ω-6 PUFA, arachidonic acid. There was no significant difference in brain tissue deposition of ω-3 PUFAs, total antioxidant capacity, or lipid peroxidation between groups. Based on the study results, ω-3 PUFAs associated with KPC resulted in tissue incorporation without changing oxidative stability.
UR - https://www.fasebj.org/doi/abs/10.1096/fasebj.23.1_supplement.543.12
M3 - Presentation
T2 - FASEB Annual Meeting
Y2 - 1 April 2011
ER -